Gene

rtn4a

ID

ZDB-GENE-030710-1

Name

reticulon 4a

Symbol

rtn4a Nomenclature History

Previous Names

rtn4
Nogo-B (1)
nogo (1)
wu:fb17a02
wu:fb22f12
wu:fd61a07
zgc:92163

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Acts upstream of or within several processes, including mesenchymal to epithelial transition; nervous system development; and sensory system development. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including heart; liver; muscle; nervous system; and pectoral fin. Orthologous to human RTN4 (reticulon 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rtn4a Human Ortholog

No data available

Associated With rtn4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003388	Reticulon

Domain Details Per Protein

Protein	Length	Reticulon
UniProtKB:Q4G5V8 InterPro	193
UniProtKB:Q4G5W2 InterPro	322
UniProtKB:A0N0A7 InterPro	319
UniProtKB:Q66HZ3 InterPro	197
UniProtKB:Q4G5W0 InterPro	254
UniProtKB:Q4G5V9 InterPro	212
UniProtKB:A0A2R8PZU6 InterPro	263
UniProtKB:F1QT89 InterPro	196
UniProtKB:A0N0A9 InterPro	196
UniProtKB:A0A2R8QI05 InterPro	197
UniProtKB:A0N0A8 InterPro	212

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	rtn4a-201 (1) Ensembl	2079 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rtn4a-202 (1) Ensembl	2138 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rtn4a-203 (1) Ensembl	1647 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rtn4a-204 (1) Ensembl	1887 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rtn4a-005 (1) Ensembl	573 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-rtn4a	polyclonal	rtn4a	IgG	Rabbit	IHC OTHR WB		4

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations