Gene

bhmt

ID
ZDB-GENE-030131-947
Name
betaine-homocysteine methyltransferase
Symbol
bhmt Nomenclature History
Previous Names
  • hm:zehn2153
  • wu:fb53h01
  • wu:fb63c08
  • wu:fj64d01
  • zgc:123027
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Is predicted to enable betaine-homocysteine S-methyltransferase activity. Involved in amino-acid betaine catabolic process. Acts upstream of or within digestive system development and type B pancreatic cell development. Predicted to be located in cytoplasm. Is expressed in hepatocyte; liver; yolk; and yolk syncytial layer. Orthologous to several human genes including BHMT (betaine--homocysteine S-methyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Yang et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bhmt Human Ortholog
No data available
Associated With bhmt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003726 Homocysteine-binding domain
Family IPR017226 Betaine-homocysteine S-methyltransferase, BHMT
Homologous_superfamily IPR036589 Homocysteine-binding domain superfamily
Domain Details Per Protein
Protein Length Betaine-homocysteine S-methyltransferase, BHMT Homocysteine-binding domain Homocysteine-binding domain superfamily
UniProtKB:F1QU55 400
UniProtKB:A0A2R8PWR1 392
UniProtKB:Q32LQ4 400
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bhmt monoclonal Mouse
  • IHC
5
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations