Gene

sulf2b

ID
ZDB-GENE-030131-775
Name
sulfatase 2b
Symbol
sulf2b Nomenclature History
Previous Names
  • sulf2a (1)
  • sulf2l
  • si:dkeyp-84g9.1
  • wu:fb48e04 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to be involved in several processes, including glomerular basement membrane development; positive regulation of vascular endothelial growth factor production; and regulation of signal transduction. Predicted to localize to cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including central nervous system; head; neural rod; segmental plate; and somite. Orthologous to human SULF2 (sulfatase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Schenk et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sulf2b Human Ortholog
No data available
Associated With sulf2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR024607 Sulfatase, conserved site
Domain IPR000917 Sulfatase, N-terminal
Domain IPR024609 Extracellular sulfatase, C-terminal
Family IPR014615 Extracellular sulfatase
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily Extracellular sulfatase Extracellular sulfatase, C-terminal Sulfatase, conserved site Sulfatase, N-terminal
UniProtKB:A0A8M9PKK2 1293
UniProtKB:A0A8M9P505 867
UniProtKB:A0A8M9PSW4 881
UniProtKB:Q6EF98 885
UniProtKB:A0A8M3B5Z5 1179
UniProtKB:A0A8M6YXM3 1044
UniProtKB:A0A8M9PKK6 856
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations