Gene
ahsa1b
- ID
- ZDB-GENE-030131-664
- Name
- AHA1, activator of heat shock protein ATPase homolog 1b
- Symbol
- ahsa1b Nomenclature History
- Previous Names
-
- ahsa1l
- id:ibd5076
- wu:fb38h08
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable ATPase activator activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; gonad; head; heart; and otic vesicle. Orthologous to several human genes including AHSA1 (activator of HSP90 ATPase activity 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Xiao et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013538 | Activator of Hsp90 ATPase homologue 1/2-like, C-terminal |
| Domain | IPR015310 | Activator of Hsp90 ATPase AHSA1-like, N-terminal |
| Homologous_superfamily | IPR023393 | START-like domain superfamily |
| Homologous_superfamily | IPR036338 | Activator of Hsp90 ATPase, Aha1 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Activator of Hsp90 ATPase, Aha1 | Activator of Hsp90 ATPase AHSA1-like, N-terminal | Activator of Hsp90 ATPase homologue 1/2-like, C-terminal | START-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q7SXN3 | InterPro | 338 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ahsa1b-201
(1)
|
Ensembl | 1,609 nt | ||
| ncRNA |
ahsa1b-002
(1)
|
Ensembl | 859 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | RP71-40K24 | ZFIN Curated Data | |
| Contains | SNP | rs3729451 | ZFIN Curated Data | |
| Encodes | EST | eu180 | Thisse et al., 2005 | |
| Encodes | EST | fb38h08 | ||
| Encodes | EST | ibd5076 | ||
| Encodes | cDNA | MGC:66167 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191549 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_212602 (1) | 1632 nt | ||
| Genomic | GenBank:BX465227 (1) | 161395 nt | ||
| Polypeptide | UniProtKB:Q7SXN3 (1) | 338 aa |
- Xiao, H., Wang, H., He, Q., Zhou, J., Du, S. (2022) Gene expression and functional analysis of Aha1a and Aha1b in stress response in zebrafish. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 262:110777
- Tastan Bishop, O., Edkins, A.L., and Blatch, G.L. (2014) Sequence and domain conservation of the coelacanth Hsp40 and Hsp90 chaperones suggests conservation of function. Journal of experimental zoology. Part B, Molecular and developmental evolution. 322(6):359-78
- Yang, L., Kemadjou, J.R., Zinsmeister, C., Legradi, J., Bauer, M., Muller, F., Pankratz, M., Jakel, J., and Straehle, U. (2007) Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome biology. 8(10):R227
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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