Gene

traf6

ID
ZDB-GENE-030131-5735
Name
TNF receptor-associated factor 6
Symbol
traf6 Nomenclature History
Previous Names
  • fi15f02
  • wu:fi15f02
  • zgc:63704
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have tumor necrosis factor receptor binding activity and ubiquitin-protein transferase activity. Involved in several processes, including innate immune response; neutrophil chemotaxis; and response to virus. Predicted to localize to cytoplasm. Is expressed in central nervous system; gill; heart; immune system; and liver. Orthologous to human TRAF6 (TNF receptor associated factor 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Aripaka et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With traf6 Human Ortholog
No data available
Associated With traf6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001293 Zinc finger, TRAF-type
Domain IPR001841 Zinc finger, RING-type
Domain IPR002083 MATH/TRAF domain
Domain IPR027139 TNF receptor-associated factor 6, C3HC3D-type RING zinc finger
Domain IPR037309 TNF receptor-associated factor 6, MATH domain
Family IPR012227 TNF receptor-associated factor TRAF, metazoa
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length MATH/TRAF domain TNF receptor-associated factor 6, C3HC3D-type RING zinc finger TNF receptor-associated factor 6, MATH domain TNF receptor-associated factor TRAF, metazoa TRAF-like Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site Zinc finger, TRAF-type
UniProtKB:Q6IWL4 542
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-traf6
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations