Gene

tpte

ID
ZDB-GENE-030131-5503
Name
transmembrane phosphatase with tensin homology
Symbol
tpte Nomenclature History
Previous Names
  • Dr-VSP (1)
  • tpip (1)
  • wu:fd20e11
  • wu:fi24b06
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Exhibits ion channel activity and phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity. Involved in phosphatidylinositol dephosphorylation. Predicted to localize to integral component of membrane. Is expressed in blood vessel; pleuroperitoneal region; and ventral mesoderm. Orthologous to several human genes including TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpte Human Ortholog
No data available
Associated With tpte Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000340 Dual specificity phosphatase, catalytic domain
Domain IPR000387 Tyrosine-specific protein phosphatases domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Domain IPR005821 Ion transport domain
Domain IPR014020 Tensin phosphatase, C2 domain
Domain IPR029023 Tensin-type phosphatase domain
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain superfamily Dual specificity phosphatase, catalytic domain Ion transport domain Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Tensin phosphatase, C2 domain Tensin-type phosphatase domain Tyrosine-specific protein phosphatases domain Voltage-dependent channel domain superfamily
UniProtKB:F1QG29 511
UniProtKB:B3IUN7 511
UniProtKB:Q4V9E4 511
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations