Gene
setb
- ID
- ZDB-GENE-030131-433
- Name
- SET nuclear proto-oncogene b
- Symbol
- setb Nomenclature History
- Previous Names
-
- wu:fb30g11
- wu:fd16c08
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Involved in neuromast development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Is expressed in several structures, including digestive system; nervous system; optic cup; otic vesicle; and tail bud. Orthologous to human SET (SET nuclear proto-oncogene).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, autosomal dominant 58 | 618106 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NAP-like superfamily | Nucleosome assembly protein (NAP) |
|---|---|---|---|
|
UniProtKB:Q6TGU0
|
275 | ||
|
UniProtKB:A0A8M2B801
|
268 |
Interactions and Pathways
No data available
Plasmids
No data available