ZFIN is now using GRCz12tu for Genomic Data

Gene

grhl1

ID

ZDB-GENE-030131-3665

Name

grainyhead-like transcription factor 1

Symbol

grhl1 Nomenclature History

Previous Names

fc49a04
wu:fc49a04

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including desmosome organization; epiboly; and inner ear development. Located in cytoplasm. Is expressed in several structures, including epidermal cell; head; integument; pronephric duct; and sensory system. Orthologous to human GRHL1 (grainyhead like transcription factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Liu et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With grhl1 Human Ortholog

No data available

Associated With grhl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007604	CP2 transcription factor
Family	IPR040167	Transcription factor CP2-like

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A286YAF2	InterPro	601
UniProtKB:E7FCE3	InterPro	613
UniProtKB:A0A8M9P024	InterPro	575
UniProtKB:A0A8M6YT08	InterPro	566

Transcripts

Genome Browsers

NCBI Map Viewer

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	grhl1-202 (1) Ensembl	Ensembl	2,069 nt	Select Tool ZFIN BLAST
mRNA	grhl1-204 (1) Ensembl	Ensembl	586 nt	Select Tool ZFIN BLAST
mRNA	grhl1-206 (1) Ensembl	Ensembl	2,171 nt	Select Tool ZFIN BLAST
mRNA	grhl1-207 (1) Ensembl	Ensembl	2,054 nt	Select Tool ZFIN BLAST
ncRNA	grhl1-003 (1) Ensembl	Ensembl	539 nt	Select Tool ZFIN BLAST
ncRNA	grhl1-004 (1) Ensembl	Ensembl	611 nt	Select Tool ZFIN BLAST
ncRNA	grhl1-005 (1) Ensembl	Ensembl	302 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations