Gene

stx4

ID

ZDB-GENE-030131-2455

Name

syntaxin 4

Symbol

stx4 Nomenclature History

Previous Names

si:dkey-220f10.3
wu:fc08c10
zgc:56272 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to localize to several cellular components, including SNARE complex; presynaptic active zone membrane; and synaptic vesicle. Orthologous to human STX4 (syntaxin 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6901547 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Perl et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stx4 Human Ortholog

No data available

Associated With stx4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006012	Syntaxin/epimorphin, conserved site
Domain	IPR000727	Target SNARE coiled-coil homology domain
Domain	IPR006011	Syntaxin, N-terminal domain
Family	IPR045242	Syntaxin
Homologous_superfamily	IPR010989	SNARE