Gene

atp6ap1b

ID
ZDB-GENE-020423-2
Name
ATPase H+ transporting accessory protein 1b
Symbol
atp6ap1b Nomenclature History
Previous Names
  • atp6ap1
  • atp6s1
  • bbl
  • bleached blond
  • etID36826.23 (1)
  • fb33b05
  • wu:fb33b05 (1)
  • zgc:103523
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have proton-transporting ATP synthase activity, rotational mechanism and proton-transporting ATPase activity, rotational mechanism. Involved in several processes, including Kupffer's vesicle development; pigment granule organization; and retinal pigment epithelium development. Localizes to plasma membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in several structures, including Kupffer's vesicle; digestive system; forerunner cell group; integument; and pleuroperitoneal region. Orthologous to human ATP6AP1 (ATPase H+ transporting accessory protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
24 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp6ap1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 47 Alliance Immunodeficiency 47 300972
Associated With atp6ap1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008388 V0 complex accessory subunit Ac45
Domain Details Per Protein
Protein Length V0 complex accessory subunit Ac45
UniProtKB:A2AR67 459
UniProtKB:Q5U3H5 459
UniProtKB:Q8JIU5 459
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-atp6ap1 polyclonal IgG Rabbit
  • IHC
  • WB
Sigma-Aldrich
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations