Gene
cp
- ID
- ZDB-GENE-010522-1
- Name
- ceruloplasmin
- Symbol
- cp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Is predicted to enable oxidoreductase activity. Involved in iron ion homeostasis and iron ion transport. Acts upstream of or within copper ion transport. Located in cytoplasm and nucleus. Is expressed in digestive system; female organism; liver and biliary system; male organism; and yolk syncytial layer. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 90 figures from 57 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55445 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Choksi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| aceruloplasminemia | Alliance | Cerebellar ataxia | 604290 |
| aceruloplasminemia | Alliance | Hemosiderosis, systemic, due to aceruloplasminemia | 604290 |
| aceruloplasminemia | Alliance | [Hypoceruloplasminemia, hereditary] | 604290 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cupredoxin | Multicopper oxidase, copper-binding site | Multicopper oxidases, conserved site |
|---|---|---|---|---|
|
UniProtKB:F1Q8N4
|
194 | |||
|
UniProtKB:F1RBQ0
|
193 | |||
|
UniProtKB:Q6P3G1
|
1087 | |||
|
UniProtKB:Q7ZU12
|
1087 | |||
|
UniProtKB:Q90ZT2
|
626 |
Interactions and Pathways
No data available
Plasmids
No data available