ZFIN Fish: AB + MO2-med13b

ZFIN ID: ZDB-FISH-170517-12

ZFIN ID: ZDB-FISH-170517-12

Fish name:	AB + MO2-med13b
Genotype:	AB
Targeting Reagent:	MO2-med13b

HUMAN DISEASE MODELED by AB + MO2-med13b
No data available

GENE EXPRESSION
Gene expression in AB + MO2-med13b

RNA expression

Expressed Gene	Structure	Conditions	Figures
fgfr3	diencephalon midbrain hindbrain boundary	standard conditions	Fig. 5 from Utami et al., 2014
isl1a	hypothalamus (not) retinal ganglion cell ventral telencephalon	standard conditions	Fig. 4 from Utami et al., 2014
sox10	cranial neural crest cell	standard conditions	Fig. 4 from Utami et al., 2014
sp8a	motor neuron olfactory placode	standard conditions	Fig. 5 from Utami et al., 2014

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in AB + MO2-med13b

Phenotype	Conditions	Figures
ceratohyal cartilage deformed, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
ceratohyal cartilage mislocalised posteriorly, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
cranial neural crest cell sox10 expression mislocalised, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
cranial neural crest cell mislocalised, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
diencephalon fgfr3 expression increased amount, abnormal	standard conditions	Fig. 5 from Utami et al., 2014
eye decreased size, abnormal	standard conditions	Fig. 3 from Utami et al., 2014
head hypoplastic, abnormal	standard conditions	Fig. 3 from Utami et al., 2014
hypothalamus isl1a expression decreased amount, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
midbrain hindbrain boundary fgfr3 expression increased amount, abnormal	standard conditions	Fig. 5 from Utami et al., 2014
motor neuron sp8a expression increased amount, abnormal	standard conditions	Fig. 5 from Utami et al., 2014
neural crest cell migration decreased process quality, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
olfactory placode sp8a expression increased amount, abnormal	standard conditions	Fig. 5 from Utami et al., 2014
pericardium edematous, abnormal	standard conditions	Fig. 3 from Utami et al., 2014
retinal ganglion cell isl1a expression absent, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
ventral telencephalon isl1a expression decreased amount, abnormal	standard conditions	Fig. 4 from Utami et al., 2014
whole organism anterior-posterior axis increased curvature, abnormal	standard conditions	Fig. 3 from Utami et al., 2014

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