ZFIN ID: ZDB-FISH-160629-1
Fish name: AB + MO4-thraa
Genotype: AB
Targeting Reagent: MO4-thraa
HUMAN DISEASE MODELED by AB + MO4-thraa
Human Disease Conditions Citations
hypothyroidism standard conditions Marelli et al., 2016
GENE EXPRESSION
Gene expression in AB + MO4-thraa
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab-T4 standard conditions Fig. 7 with image from Marelli et al., 2016
Reporter gene expression No data available
PHENOTYPE
Phenotype in AB + MO4-thraa
Phenotype Conditions Figures
brain dio3a expression decreased amount, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
embryo development decreased rate, abnormal standard conditions Fig. S4 with image from Marelli et al., 2016
head decreased size, abnormal standard conditions Fig. 3 with imageFig. 5 with image from Marelli et al., 2016
hypophysis dio2 expression increased amount, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
hypophysis dio2 expression increased distribution, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
hypophysis cell decreased volume, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
mandibular arch skeleton has fewer parts of type cartilage element, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
pericardium edematous, abnormal standard conditions Fig. 3 with imageFig. 5 with image from Marelli et al., 2016
pronephric duct dio3b expression decreased amount, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
pronephric duct proximal region dio3b expression absent, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
pronephric duct proximal region dio3a expression absent, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
swim bladder uninflated, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
thyroid follicle slc5a5 expression decreased amount, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle tg expression decreased amount, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
thyroid follicle ab-t4 labeling decreased distribution, abnormal standard conditions Fig. 7 with image from Marelli et al., 2016
thyroid follicle cell decreased volume, abnormal standard conditions Fig. 6 with image from Marelli et al., 2016
ventricular system edematous, abnormal standard conditions Fig. 3 with imageFig. 5 with image from Marelli et al., 2016
ventricular system hydrocephalic, abnormal standard conditions Fig. 5 with image from Marelli et al., 2016
whole organism dead, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016
whole organism dio3a expression decreased amount, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
whole organism dio3b expression decreased amount, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
whole organism decreased length, abnormal standard conditions Fig. 3 with imageFig. S4 with image from Marelli et al., 2016
whole organism decreased pigmentation, abnormal standard conditions Fig. 3 with image from Marelli et al., 2016
whole organism has fewer parts of type thyroid follicle, abnormal standard conditions Fig. 7 with image from Marelli et al., 2016
whole organism dio2 expression increased amount, abnormal standard conditions Fig. 8 with image from Marelli et al., 2016
whole organism lacks parts or has fewer parts of type pectoral fin, abnormal standard conditions Fig. S5 with image from Marelli et al., 2016

CITATIONS  (1)