FIGURE

Fig. 3

ID

ZDB-FIG-250118-51

Publication

Cero et al., 2024 - Profiling the cancer-prone microenvironment in a zebrafish model for MPNST

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Fig. 3

Pathway and gene set enrichment analyses identify gene expression changes that uniquely characterize the cancer versus precancerous microenvironment.

A Canonical pathways identified by Ingenuity Pathways Analysis (IPA) that were predicted to be activated exclusively in the comparison of cancer versus precancerous microenvironments (MEs). B Genetic upstream regulators associated with predicted pathway activation as identified by IPA that were significantly upregulated exclusively in the comparison of cancer versus precancerous MEs. C Gene set enrichment analysis (GSEA) identifies six hallmark gene sets with a positive normalized enrichment score (NES) exclusively in the comparison of cancer versus precancerous MEs. D GSEA identifies 6 hallmark gene sets with a negative NES in the comparison of precancerous versus control MEs, but a positive NES in the comparison of cancer versus control MEs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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