FIGURE

Figure 1

ID

ZDB-FIG-241115-116

Publication

Zhao et al., 2024 - The Glutamine Synthetases Are Required for Sensory Hair Cell Formation and Auditory Function in Zebrafish

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Figure 1

Phylogenetic analysis of Glul across diverse species and the expression patterns of the Glul gene family in zebrafish. (A) The MEGA software (Version 11.0.13) was utilized to construct a phylogenetic tree based on amino acid sequences, encompassing a diverse range of species including H. sapiens, P. troglodytes, M. mulatta, C. lupus, B. taurus, M. musculus, R. norvegicus, G. gallus, D. rerio, D. melanogaster, A. gambiae, C. elegans, S. cerevisiae, K. lactis, E. gossypii, S. pombe, N. crassa, A. thaliana, O. sativa, and X. tropicalis. Branches of the same color are closer. Whole-mount in situ hybridization (WISH) was performed using glula, glulb, and glulc probes in wild-type zebrafish. (B) The results demonstrated that the expression of the glula gene was observed specifically in the otic vesicle. Green arrowheads indicate otic vesicle. Boxes indicate the magnified regions. (C) while the glulb gene exhibited expression in both the otic vesicle and lateral line. Green arrowheads indicate otic vesicle and neuromasts. Boxes indicate the magnified regions. (D) Conversely, no significant signal was detected for the glulc gene.

Expression Data

Genes:	glula glulb glulc
Fish:	AB
Anatomical Terms:	brain caudal vein plexus inner ear nervous system neuromast notochord otic vesicle
Stage Range:	Prim-5 to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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