FIGURE

Figure 3

ID

ZDB-FIG-241025-3

Publication

Jones et al., 2024 - Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response

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Figure 3

MZ-fam83fa^−/− mutant embryos hatch earlier than WT. (a) Estimated mean hatching times across replicates (n = 3) for WT (red), MZ-fam83fa^−/− KO1 (green) and MZ-fam83fa^−/− KO2 (blue). Log-odds of hatching is plotted over time (hpf); where the curves cross 0.0 on the y-axis, 50% of the embryos have hatched. p < 0.0001, proportional odds logistic regression. (b) Common effect size across replicates shown as predicted mean hatching hour. Note that MZ-fam83fa^−/− KO1 embryos hatch ~10 h earlier than WT. (c) Examples of still images from time-lapse movies used to determine hatching times.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fam83fa^{fci401/fci401} (AB) fam83fa^{fci402/fci402} (AB)
Observed In:	hatching whole organism
Stage:	Pec-fin

Phenotype Detail

Acknowledgments

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