FIGURE

Fig. 3

ID

ZDB-FIG-241015-13

Publication

Ling et al., 2024 - Establishment of a Diamond-Blackfan anemia like model in zebrafish

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Fig. 3

No alterations in primitive hematopoietic lineages in epoaszy8. (A) βe1-globin WISH (indicated by red triangular arrowheads) identified erythroid progenitor cells at 23-hpf in epoaszy8 compared with WT (Fisher's exact test, n > 10, ns: no significance). (B) gata1a WISH (indicated by red triangular arrowheads) identified erythroid progenitor cells at 22-hpf in epoaszy8 compared with WT (Fisher's exact test, n ≥ 6, ns: no significance). (C and D) pu.1 WISH (C) identified primitive myeloid cells at 23 hpf in epoaszy8 compared with WT (Student's t-test, n > 10, mean ± SD, ns: no significance). (E) O-dianisidine staining (indicated by red triangular arrowheads) identified hemoglobin at 2 dpf.

Expression Data

Genes:	gata1a hbbe1.1 spi1b
Fish:	epoa^szy8/szy8
Anatomical Terms:	erythroid lineage cell myeloid cell
Stage:	26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	epoa^szy8/szy8
Observed In:	erythrocyte development primitive hemopoiesis
Stage:	26+ somites

Phenotype Detail

Acknowledgments

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