FIGURE

Fig. 6

ID

ZDB-FIG-240801-6

Publication

Sande-Melon et al., 2024 - Development of a hepatic cryoinjury model to study liver regeneration

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Fig. 6

Biliary epithelial cells (BECs) and endothelial cells (ECs) recover upon cryoinjury. (A-F″) Whole-mount imaging of GreenLantern+ hepatocytes and Anxa4+ biliary epithelial cells from sham-operated (A-A″) or injured (B-F″) livers at the indicated stages. The outlined areas are shown at higher magnification. (G) Mean intensity profile of Anxa4 within the IA at the designated stages is represented by individual lines for each sample, with the IA delineated in grey (n=4 throughout). (H-M″) Whole-mount acquisitions of GFP+ ECs from sham-operated (H-H″) or injured (I-M″) livers at the indicated stages. The outlined areas are shown at higher magnification. (N) Mean intensity profile of fli1a:nGFP within the IA at the designated stages is represented by individual lines for each sample, with the IA delineated in grey (n=4 throughout). Dashed yellow line indicates the border zone of the injured area; IA, injured area. Scale bars: 500 µm.

Expression Data

Genes:	EGFP mGreenLantern
Antibody:	Ab-2F11
Fish:	uom306Tg/uom306Tg y7Tg/y7Tg
Condition:	cryoablation: liver
Anatomical Terms:	liver liver endothelial cell liver and biliary system regenerating tissue regenerating tissue endothelial cell
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	uom306Tg/uom306Tg y7Tg/y7Tg
Condition:	cryoablation: liver
Observed In:	liver endothelial cell liver and biliary system regenerating tissue liver regeneration regenerating tissue endothelial cell vascular endothelium liver regeneration
Stage:	Adult

Phenotype Detail

Acknowledgments

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