Fig. 3
- ID
- ZDB-FIG-240112-9
- Publication
- Tavakoli et al., 2023 - Transplantation-based screen identifies inducers of muscle progenitor cell engraftment across vertebrate species
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NFA and LPA show an additive effect on muscle progenitor cell engraftment efficiency in zebrafish (A) Engraftment efficiency in prkdc-mutant recipient zebrafish (4–8 months old) of ZeMPCs treated for 4 h with the indicated concentrations and combinations of NFA and LPA, or with DMSO (vehicle) as control. (B) The potency of engrafting cells (1/cell frequency) from (A) was estimated with ELDA. Error bars represent the upper and lower confidence intervals. (C) Statistical differences (p values) between groups were determined with ELDA. DMSO concentration for all groups including experimental controls and as vehicle for NFA and LPA was 0.1%. n = 10 fish per cell number dose and 30 per treatment (∗p < 0.05; limiting dilution assay). |