FIGURE

Fig. 3

ID

ZDB-FIG-230912-17

Publication

Mathavarajah et al., 2023 - PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Origins of PML-like exon 9 (Plex9) and TREX1 genes. (A) Teleost plex9 genes show synteny to the spotted gar pml locus. Similarly coloured genes represent homologs between species. The chromosome where the pml locus is found in each species is indicated on the right. The intervening arrows with numbers indicate the number of intervening adjacent genes that exist between the homologous genes not found in the syntenic region. (B) Plex9 homologs resemble both TREX1/2 and PML exonucleases but are related to PML exonucleases. A maximum likelihood tree was constructed using Plex9, PML CDE and TREX1/2 protein sequences. While the TREX1 proteins cluster with TREX2, sequences for Plex9 cluster with PML CDE sequences. Bootstrap values are indicated beside each node. Ultrafast bootstrap values are shown as numbers if <85% and indicated with solid dots on branches if >85%. Branch lengths indicate the expected number of amino acid substitutions per site.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nucleic Acids Res.