FIGURE

Figure 7

ID

ZDB-FIG-230724-55

Publication

Cacialli et al., 2023 - Minichromosome maintenance protein 10 (mcm10) regulates hematopoietic stem cell emergence in the zebrafish embryo

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Figure 7

p53 knockdown rescues the loss of HSCs in mcm10-deficient embryos

(A) runx1 expression at 28 hpf in mcm10^−/− mutant embryos and their siblings, either injected with control or p53 morpholinos.

(B) runx1 expression at 28 hpf in embryos co-injected with mcm10 and p53 morpholinos.

(C) Statistical analysis was completed using Fisher’s exact test. ^∗p < 0.01; ^∗∗p < 0.001; ^∗∗∗p < 0.0001 (n = number of total embryos from three independent experiments). Scale bars: 200 μm (A), 100 μm (B).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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