FIGURE

Fig. 7

ID

ZDB-FIG-230211-27

Publication

Zhang et al., 2023 - SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway

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Fig. 7

S-protein induces the expression of senescence-associated factors in the zebrafish retina. A H&E analysis of day 2 zebrafish retina post injection of PBS or 6.3 ng S-protein. B Quantitative RT-PCR measuring the expression of P53, P21, P16, IL-1β, IL-6, IL-8, ICAM1, VEGF-A, BIP, CHOP, ATF3, ATF6 in day 2 and day 3 recovered zebrafish retina post injection of S-proteins. The data showed mean ± SD, n = 6. The unpaired student t-test was used for statistical analysis. *p < 0.05, **p < 0.01

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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