FIGURE
Fig. 2
- ID
- ZDB-FIG-220706-103
- Publication
- Lozano-Gil et al., 2022 - Gasdermin E mediates pyroptotic cell death of neutrophils and macrophages in a zebrafish model of chronic skin inflammation
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 2
Fig. 2. Inhibition of the neutrophil inflammasome leads to an increase in the number of neutrophils in zebrafish with skin inflammation. (A) Schematic showing the zebrafish lines used to inhibit neutrophil inflammasome. The offspring were screened using fluorescent green heart marker of the Tg(uas:ascĪCARD-GFP). (B, C) One-cell stage zebrafish eggs were microinjected with control or spint1a crRNA/Cas9 complexes. At 3 dpf, neutrophils (B) and erythrocytes (C) were stained with neutral red, Sudan black and o-dianisidine, respectively. ****p < 0.0001; n.s., non-significant. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Dev. Comp. Immunol.