FIGURE

Fig 3

ID
ZDB-FIG-220131-103
Publication
Sveinsdóttir et al., 2022 - Motility phenotype in a zebrafish vmat2 mutant
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Fig 3

Treatment of vmat2 larvae with a dopamine agonist or precursor.

Homozygous vmat2 (HOM) larvae were treated with three different concentrations (1μM, 10μM and 100μM) of pramipexole (A, C) or L-dopa (B, D) and compared to untreated larvae (naïve). Pramipexole and L-Dopa did not significantly alter the peak velocity at the onset of lights-off (A, B). Pramipexole (C) reduced the distance moved during lights-on significantly for all three concentrations whereas L-Dopa (D) increased it significantly for 1μM and 10μM. Naïve wild type (WT) larvae are included in the data for visual comparison. For values and statistics see Tables ​Tables11 and ​and22.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Conditions:
Observed In:
Stage: Day 6

Phenotype Detail
Acknowledgments
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