FIGURE

Figure 5

ID
ZDB-FIG-211120-57
Publication
Rodríguez-Ortiz et al., 2021 - Mutants of the Zebrafish K+ Channel Hcn2b Exhibit Epileptic-like Behaviors
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Figure 5

Seizures induced by flashlights in the hcn2b−/− mutant. During dark-light transitions, about 7% of adult hcn2b−/− mutants exhibited behavioral seizure activity. (A) First, fish increased their swimming activity (Stage I); then, they showed a rapid “whirlpool-like” circling swimming behavior (Stage II); finally, they exhibited a series of brief clonus-like convulsions that led to a loss of posture and immobility (Stage III). (B) Snap shot sequences of each stage of the seizures caused by flashlight in the hcn2b−/− mutant zebrafish. Images taken from Video S2.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Adult

Phenotype Detail
Acknowledgments
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