FIGURE

FIGURE 1

ID
ZDB-FIG-211118-1
Publication
Xu et al., 2021 - Overexpression of Lifeact-GFP Disrupts F-Actin Organization in Cardiomyocytes and Impairs Cardiac Function
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FIGURE 1

Analysis of congenital cardiomyopathy in smyd1bsa15678 mutant using Tg(myl7:Lifeact-GFP) transgenic zebrafish model. (A–D) Morphology and Lifeact-GFP expression in the heart region of WT Tg(myl7:Lifeact-GFP)mb21 (A,B), and smyd1bsa15678; Tg(myl7:Lifeact-GFP)mb21 mutant (C,D) transgenic larvae at 72 hpf. Pericardial edema is indicated by arrow in smyd1bsa15678; Tg(myl7:Lifeact-GFP)mb21 transgenic mutant larvae (C). Scale bars: 250 μm. (E–J) Actin think filaments in cardiomyocytes revealed by Lifeact-GFP (E,H) and phalloidin staining (F,I) in WT Tg(myl7:Lifeact-GFP)mb21 (E–G), and smyd1bsa15678; Tg(myl7:Lifeact-GFP)mb21 transgenic mutant (H–J) embryos at 72 hpf. (G,J) are merged pictures of (E,F,H,I), respectively. Scale bars: 50 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol