FIGURE

Fig. 4

ID

ZDB-FIG-210821-32

Publication

Hosseini et al., 2021 - The adapter protein Myd88 plays an important role in limiting mycobacterial growth in a zebrafish model for tuberculosis

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Fig. 4

Granuloma structures in myd88^-/- larvae consist mainly of extracellular Mm. a TEM image of a granuloma in representative myd88^+/+ larvae, showing the necrotic centre (N) and aggregates of Mm in the immune cells. b,c Higher magnification of regions indicated in (a), showing infected cells (arrowheads) and extracellular Mm (arrows). d TEM image of a granuloma in representative myd88^-/- larvae showing the area with extracellular Mm (black line). e,f Higher magnification of region indicated in (d), showing extracellular bacteria and infected cells (arrowheads). n = 3 per group, the scale bars in (a)–(d) (20 μm) and in (b)–(c) and (e)–(f) (10 μm)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	myd88^{hu3568/hu3568}
Condition:	bacterial treatment by injection: Mycobacterium marinum M
Observed In:	defense response to bacterium
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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