FIGURE

FIGURE 8

ID
ZDB-FIG-210530-22
Publication
Gong et al., 2021 - Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish
Other Figures
(all 8)
All Figure Page
Back to All Figure Page
FIGURE 8

Knocking out of claudin h caused the defects of otic vesicle and impaired the development of cristae hair cells and neuromast hair cells. (A) Imaging analysis of otic vesicle and cristae hair cells in control and claudin h mutants at 96 hpf. The yellow dotted line marked the boundary of the otic vesicle. (B) The statistical analysis of otic vesicle area in control and claudin h mutants at 96 hpf. (C,D) The statistical analysis of the number of different cristae hair cells and the cilia lengths in control and claudin h mutants at 96 hpf. (E) The imaging analysis of control and claudin h mutants at 96 hpf in bright field and fluorescent field. (F) Confocal imaging analysis of L1 hair cell clusters in the posterior lateral line of control and claudin h mutants at 96 hpf. (G,H) Quantification of the number of hair cell clusters and the number of hair cells per L1 neuromast in the posterior lateral line of control and claudin h mutants at 96 hpf. Values with *, ***, and ****above the bars are significantly different (P < 0.05, P < 0.001, and P < 0.0001, respectively).
Expression Data
Gene:
Fish:
Anatomical Terms:
Stage: Day 4

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In: (all 9)
Stage: Day 4

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.