FIGURE

Fig. 5

ID

ZDB-FIG-210419-38

Publication

Wang et al., 2021 - Aquaporins Have Regional Functions in Development of Refractive Index in the Zebrafish Eye Lens

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Fig. 5

Loss of Aqp0a and Aqp0b alters lens maximum refractive index growth. Lens refractive index as a function of lens diameter (A) and age (dpf) (B) for WT, aqp0a−/−, aqp0b−/−, and double aqp0a−/−/aqp0b−/− mutants. Lens maximum refractive index growth followed a similar trend and plateaued close to 1.58 at lens diameters over ∼650 µm (A) and in fish over ∼40 dpf (B). Double aqp0a−/−/aqp0b−/− mutant lens maximum refractive index growth did not plateau and reached a maximum attained value of ∼1.57 at lens diameters of ∼900 µm (A) and fish over ∼150 dpf (B).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)
Observed In:	lens
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.