FIGURE

Figure 4

ID
ZDB-FIG-210301-103
Publication
Brastrom et al., 2021 - Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia
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Figure 4

Exogenous sox2 can suppress rbm24a-associated microphthalmia. (A) Uninjected 4 dpf embryo with wild type morphology, (A’) detail of eye in A. (B) Knockdown of rbm24a at low doses leads to microphthalmia, (B’) detail of eye in B. (C) Sequential injection of rbm24a morpholino and sox2 RNA results in a phenotype more similar to wild type than rbm24a morphant, (C’) detail of eye in C. (D) Injection of sox2 RNA alone results in wild type morphology, (D’) detail of eye in D. (E) Graph of phenotypes. Images taken at 33×.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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