ZFIN Figure: Kröll-Hermi et al., 2020, Fig. 6

ZFIN ID: ZDB-FIG-210225-59

ZFIN ID: ZDB-FIG-210225-59

Kröll-Hermi et al., 2020 - Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress. EMBO Molecular Medicine 12(7):e11861 Full text @ EMBO Mol. Med.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	WT + CRISPR2-psmc3 WT + MO1-psmc3 nkgsaizGFF539AGt + MO1-psmc3
Knockdown Reagents:	CRISPR2-psmc3 MO1-psmc3
Observed In:	lateral crista kinocilium lens semicircular canal semicircular canal fusion
Stage:	Day 4

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + CRISPR2-psmc3	standard conditions	Day 4	lateral crista kinocilium amount, abnormal
		Day 4	lens opacity, abnormal
		Day 4	semicircular canal fusion disrupted, abnormal
		Day 4	semicircular canal unfused from semicircular canal, abnormal
WT + MO1-psmc3	standard conditions	Day 4	lens opacity, abnormal
		Day 4	semicircular canal fusion disrupted, abnormal
		Day 4	semicircular canal unfused from semicircular canal, abnormal
nkgsaizGFF539AGt + MO1-psmc3	standard conditions	Day 4	semicircular canal fusion disrupted, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Mol. Med.