FIGURE

Figure 1

ID

ZDB-FIG-200718-27

Publication

Park et al., 2020 - Author Correction: 3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish

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Figure 1

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Figure 1

Predisposed liver injury in the kdsr^I105R/+ adult zebrafish. H & E staining of wild type liver (A) and heterozygous kdsr mutant liver (B). The inset depicts high resolution of the identified areas. Images shown are representative of at least 10 in total. Scale bar for A and B is 100 μm. Serum ALT test (C) in wild type and heterozygous kdsr mutant (n = 3). Relative mRNA expression of tnfa, il1b, and col1a1a (D) and sphk2, asah1a, asah1b, and asah2 (E) in wild type and kdsr^I105R/+ mutants (n = 3). Error bars indicate standard deviation of the mean. *P ≤ 0.05, **P ≤ 0.005. ALT, alanine aminotransferas.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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