FIGURE

FIGURE 1

ID

ZDB-FIG-200619-52

Publication

Mazzola et al., 2020 - Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects

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FIGURE 1

Positive correlation between NIPBL and RUNX1 expression in megakaryocytes derived from healthy donors and in bone marrow cells derived from 34 adult AML patients. A and B, Spearman's correlation between RUNX1 and RAD21 (A) or NIPBL (B) in cord blood megakaryocytes (MK) derived from healthy donors. C and D, Spearman's correlation between RUNX1 and RAD21 (C) or NIPBL (D) in bone marrow cells (BM) derived from 34 adult AML patients without aberrant RUNX1 alterations (mutations or translocations). E and F, Spearman's correlation between RUNX1 and NIPBL in 34 adult AML patients without (NPM1wt) (E) or with NPM1 mutation (NPMc+) (F). Spearman's correlation analysis showed a significant positive correlation of the ratio of RUNX1 expression only versus NIPBL, not versus RAD21,. r = Spearman's correlation coefficient

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell. Mol. Med.