ZFIN ID: ZDB-FIG-200109-17
Lin et al., 2019 - Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia. Brain : a journal of neurology   142(8):2238-2252 Full text @ Brain
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 6

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ml2Tg + MO2-ubap1 standard conditions Long-pec embryo development disrupted, abnormal
Long-pec motor neuron axon decreased length, abnormal
Long-pec somite U-shaped, abnormal
Long-pec thigmotaxis disrupted, abnormal
Long-pec whole organism curved ventral, abnormal
Day 6 whole organism dead, abnormal
Day 6 whole organism decreased life span, abnormal
ml2Tg + MO3-ubap1 standard conditions Prim-5 whole organism dead, abnormal
Prim-5 whole organism decreased life span, abnormal
Long-pec embryo development disrupted, abnormal
Long-pec motor neuron axon decreased length, abnormal
Long-pec somite U-shaped, abnormal
Long-pec thigmotaxis disrupted, abnormal
Long-pec whole organism curved ventral, abnormal
Full text @ Brain