FIGURE

Fig. 7

ID

ZDB-FIG-190808-18

Publication

Cheng et al., 2019 - Collagen triple helix repeat containing 1a (Cthrc1a) regulates cell adhesion and migration during gastrulation in zebrafish

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Fig. 7

Functional interaction between Cthrc1a and integrin β1 in axis extension. (A) Embryos were injected with CoMO, low dose of dnß1 mRNA, low dose of cthrc1MO, or a mixture of cthrc1MO and dnß1 mRNA at 1-cell stage, statistical analysis of the extent of hypoblast migration in different injected embryos was performed at bud stage, as shown in the inset image. A total of 12 embryos randomly selected from 3 independent experiments were analysed for each condition. Numbers in each column represent total embryos injected. The results are expressed as mean ± s.d. from three independent experiments (*, P < 0.05; **, P < 0.01; Student's t-test). (B–E) Representative phenotypes for each condition at 27 hpf, as indicated. Scale bar: (B–E) 500 μm.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Exp. Cell Res.