FIGURE
Figure 1: Effect of Alzheimer’s disease on NSPCs.
- ID
- ZDB-FIG-190723-2148
- Publication
- Tincer et al., 2016 - Neural stem/progenitor cells in Alzheimer's disease
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Figure 1: Effect of Alzheimer’s disease on NSPCs.
A simplified sketch showing the effects of Aβ deposition in mouse brain on stem cell proliferation, transient amplifying progenitor proliferation, neuronal differentiation and maturation. Aβ42 through infusion or transgenic APPswe/PS1 suppressed NSPC proliferation, while PDGF-driven APPswe,Ind increases the differentiation of progenitors to neurons. NSC: neural stem cell; TAP: transiently amplifying cells, IN: immature neuron. See text for details. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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