Fig. 2
- ID
- ZDB-FIG-190524-22
- Publication
- Rasouli et al., 2018 - The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling
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Cardiac contractility is required for cardiomyocyte extrusion.(A) Maximum intensity projections of confocal z-stacks of 96 hpf klf2 WT and mutant hearts, non-injected or injected with tnnt2a MO at the one-cell stage; part of ventricular outer curvature (dashed boxes) magnified on the right side of each panel. (B) Time-lapse 2D confocal images of a klf2 mutant heart during BDM treatment. Arrows point to an extruding cardiomyocyte returning to the compact layer upon inhibiting contraction; V: ventricle; At: atrium; scale bars: 50 µm (A), 10 µm (B). |
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Stage: | Day 4 |
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Stage: | Day 4 |