FIGURE

Fig. 1

ID

ZDB-FIG-180725-20

Publication

Berrun et al., 2018 - Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish

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Fig. 1

ism1 is highly expressed in hematopoietic-supportive stromal cell lines.

(A) Each stromal cell line is derived from sites of hematopoietic emergence, expansion, and maintenance in adult and embryonic zebrafish; adult zebrafish kidney stroma (ZKS, derived from the adult kidney; pink[50]), zebrafish embryonic stromal trunk (ZEST, derived from the embryonic trunk; blue[48]), and caudal hematopoietic embryonic stromal tissue (CHEST, derived from the CHT; green[49]). (B) Each stromal cell line’s transcriptome was analyzed with RNA-seq and compared to a non-hematopoietic supportive stromal cell line (ZF4); transcripts were plotted as a Venn diagram demonstrating 447 conserved transcripts. (C) ism1 transcript levels for each cell line presented as reads per kilobase of transcript per million reads mapped (RPKM). See Table 1 for genes identified in this screen.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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