FIGURE

Fig. 2

ID

ZDB-FIG-180424-51

Publication

Heffer et al., 2017 - Generation and characterization of Kctd15 mutations in zebrafish

Other Figures

(all 14)

All Figure Page

Back to All Figure Page

Fig. 2

kctd15 mutants have more melanophores.

While there is no premature appearance of melanophores in our mutants (A,B), by 5 dpf there are visibly more on the dorsal side of the head (C,D), and by 19 dpf, there is a marked increase in melanophore pigment cells both on the dorsal and lateral sides of the larvae (E,F). This increase in pigmentation is still seen at 30 dpf (G,H). Examination of transcript levels and expression patterns in 25 hpf embryos revealed an up-regulation of the early melanophore markers tyrp1a (I-K) and zgc:91968 (L-N).

Expression Data

Genes:	tyrp1a zgc:91968
Fish:	AB kctd15a^y584/y584; kctd15b^y585/y585 (AB)
Anatomical Terms:	melanocyte migratory neural crest cell
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kctd15a^y584/y584; kctd15b^y585/y585 (AB)
Observed In:	melanocyte migratory neural crest cell
Stage Range:	Prim-5 to Days 30-44

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One