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ZDB-FIG-180424-29

Publication

Uribe et al., 2017 - Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells

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Fig. S2

Ectopic expression of 25 pg of meis3 is sufficient to partially rescue gut colonization in embryos temporally lacking RA (A-D’’) Whole mount double immunochemistry shows Hu⁺/-8.3phox2bb:Kaede⁺ enteric neurons along the gut of (A-A’’) control, (B-B’’) DEAB treated larvae, (C-C’’) larvae injected with 25 pg meis3, and larvae injected with 25 pg meis3 and treated with DEAB (D-D’’). While larvae treated with DEAB from 24 to 73 hpf exhibit a severe loss of enteric neurons (B-B’’), embryos treated with DEAB also expressing 25 pg meis3 exhibit a partial rescue of enteric neuron localization along the midgut (D-D’’).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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Reprinted from Developmental Biology, 433(1), Uribe, R.A., Hong, S.S., Bronner, M.E., Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells, 17-32, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.