FIGURE

Fig. 5

ID

ZDB-FIG-180413-9

Publication

Schoppik et al., 2017 - Gaze-stabilizing central vestibular neurons project asymmetrically to extraocular motoneuron pools

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Fig. 5

Vestibular nucleus neurons labeled in Tg(−6.7FRhcrtR:gal4VP16) are necessary for both nose-up and nose-down gaze stabilization. A, Horizontal MIP of vestibular and control neurons (nVII) in rhombomeres 4–8 in Tg(−6.7FRhcrtR:gal4VP16); Tg(UAS-E1b:Kaede)^s1999t; Tg(isl1:GFP) fish before and after targeted photo-ablation of vestibular neuron cell bodies. γ = 0.5 highlights dim signal. Colors represent depth over ∼150 μm. White arrows indicate the general region of targeted cell bodies in either the vestibular nuclei (top row) or the facial nucleus (nVII). Scale bar, 150 μm. For anatomical localization, compare with the right side of Figure 1B. B, Vestibulo-ocular reflex gain preablation and postablation of vestibular neurons. C, Vestibulo-ocular reflex gain preablation and postablation of facial nucleus neurons. D, Vestibulo-ocular reflex gain wild-type siblings (WT) and fish with pharmacogenetic (nitroreductase, “nfsb”) and optogenetic ablation (Killer-Red [KR]) of neurons in Tg(−6.7FRhcrtR:gal4VP16).

Expression Data

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Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neurosci.