FIGURE

Fig. 1

ID

ZDB-FIG-180322-22

Publication

Pomreinke et al., 2017 - Dynamics of BMP signaling and distribution during zebrafish dorsal-ventral patterning

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Fig. 1

BMP signaling (pSmad1/5/9) gradient formation and simulations of five major dorsal-ventral patterning models over relevant zebrafish developmental stages (3 hr).

(A) Two-dimensional Hammer-Aitoff projections (2D maps) of pSmad1/5/9-immunostained individual wild type zebrafish embryos at different developmental stages. Embryos were imaged using light sheet microscopy (see Materials and methods for details). (B) Quantification of ventral-to-dorsal average pSmad1/5/9 distributions in one-dimensional projections of 2D maps generated for embryos at different developmental stages (n = 3 for each stage) as in (A). Error bars denote standard error. (C–G) Gradient formation kinetics simulated for Models 1–5 at relevant zebrafish developmental stages.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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