FIGURE

Fig. 1

ID

ZDB-FIG-180202-9

Publication

Madigan et al., 2017 - A Zebrafish Model of Mycobacterium leprae Granulomatous Infection

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Fig. 1

Adult zebrafish are susceptible to Mycobacterium leprae infection. A, Hematoxylin-eosin (H-E)–stained section of a granuloma in the peritoneal cavity of a wild-type adult zebrafish 7 days after infection with 5 × 10⁷ Thai53 strain M. leprae. Arrowheads indicate lymphocyte nuclei. B, Granuloma from a skin biopsy specimen from a patient with tuberculoid leprosy. The image is from the archives of the Lauro de Souza Lima Institute. C, Serial section of the granuloma in panel A, stained for acid-fast bacilli (AFB) to detect M. leprae; many bacteria are present (arrows). D, AFB-stained granuloma section from the peritoneal cavity of a similarly infected fish, 7 days after infection; few bacteria are present. Arrows indicate bacilli. Bars denote 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	bacterial treatment by injection: Mycobacterium leprae
Observed In:	granuloma formation
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Infect. Dis.