Fig. S2
- ID
- ZDB-FIG-171101-54
- Publication
- Cheng et al., 2015 - Deltex1 is inhibited by the Notch-Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation
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Her2 and Her8a specifically bind to the N-box in dtx1 promoter. a. Green fluorescence indicates EGFP expression driven by the fragment containing N-boxes, which is overlapped with HuC/D-positive neurons (red). b. The intensity of EGFP expression in HuC/D-positive cells, quantified by ImageJ, showing co-injection of N-box:EGFP with full-length her2 or her8a cRNA downregulated the expression of EGFP, whereas co-injection of a her2 or her8a construct lacking the transcription activating WRPW domain (her2 ΔWRPW or her8a ΔWRPW , respectively) with N-box:EGFP does not downregulate EGFP expression. |