FIGURE
Fig. 5
- ID
- ZDB-FIG-170914-50
- Publication
- Zoni et al., 2017 - CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer
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Fig. 5
CRIPTO knockdown reduces invasion and tumor growth of human PCa cells in vivo. (a) PC-3M-Pro4Luc2_dTomato human PCa cells with scrambled shRNA control (NT) and shCRIPTO no. 2 shRNAs were injected into the duct of Cuvier to monitor extravasation and formation of distant growth in vivo (30 embryos injected per group). (b) CRIPTO knockdown reduces whole-body tumor burden at 4 dpi (days post injection). Error bars±s.e.m. (c) CRIPTO knockdown reduces the number of extravasated cells at 1 and 4 dpi at the caudal hematopoietic tissue. Error bars±s.e.m. **P<0.01 and ***P<0.001. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Condition: | |
| Anatomical Term: | |
| Stage Range: | Protruding-mouth to Day 6 |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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