FIGURE

Fig. 9

ID

ZDB-FIG-170227-8

Publication

Lessieur et al., 2017 - The Ciliopathy Gene ahi1 Is Required for Zebrafish Cone Photoreceptor Outer Segment Morphogenesis and Survival

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Fig. 9

ahi1 is not required for ciliogenesis or transition zone protein localization. (A, B) Tg(centrin:GFP) expression (green) localized to the apical inner segments in wild-type and ahi1^lri46 mutants at 3 dpf. Zpr1 (red) was used to stain cone photoreceptors to visualize the apical boundary. (C, D) Five dpf retinas stained with acetylated tubulin (green) and Ift88 (red) showed ciliary localization of the IFT particle in wild-type and mutant animals. (E, H) The transition zone proteins Cep290 and Cc2d2a (red) exhibited punctate staining in wild-type and mutant animals. Scale bar: 20 μm.

Expression Data

Genes:	cc2d2a cep290 GFP ift88
Antibodies:	Ab1-cc2d2a Ab1-ift88 Ab1-tuba zpr-1
Fish:	WT ahi1^lri46/lri46 cu6Tg ahi1^lri46; cu6Tg
Anatomical Terms:	eye photoreceptor cell photoreceptor connecting cilium eye photoreceptor cell photoreceptor inner segment retinal cone cell photoreceptor connecting cilium
Stage Range:	Protruding-mouth to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ahi1^lri46/lri46 ahi1^lri46; cu6Tg
Observed In:	eye photoreceptor cell cilium assembly eye photoreceptor cell photoreceptor connecting cilium
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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