FIGURE

Fig. 4

ID

ZDB-FIG-161104-3

Publication

Saera-Vila et al., 2016 - Autophagy Regulates Cytoplasmic Remodeling During Cell Reprogramming in a Zebrafish Model of Muscle Regeneration

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Autophagy as an energy-providing and recycling process. (A to H) Fed and fasted fish were myectomized and treated with or without CQ. Proliferation was visualized at 24 hpi staining for EdU; the inset shows the differential interference contrast image. (I) Quantification of proliferation showed that both fasting and CQ treatment reduced proliferation in the regenerating LR muscle; values are averages ± SEM (Student t test, *, P < 0.05; **, P < 0.01; n = 4). (J) To better illustrate the interaction of feeding condition and CQ treatment, proliferation values were normalized to the 0 mM CQ value of each group showing that CQ treatment reduced proliferation similarly in both fed and fasted fish. Values are averages ± SEM (Student t test; *, P < 0.05, n = 4).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: chloroquine, resection: lateral rectus fasting, resection: lateral rectus chemical treatment by environment: chloroquine, fasting, resection: lateral rectus
Observed In:	lateral rectus cell population proliferation regenerating tissue cell population proliferation
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Autophagy