FIGURE

Fig. 7

ID

ZDB-FIG-161018-26

Publication

Olsen et al., 2016 - G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis

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Fig. 7

The Retinal Defects of g9a, znf644a, and znf644b Morphants Are Recapitulated in the Midbrain

(A) WISH assays monitoring ccnd1 expression in WT, znf644a, or znf644b morphant midbrain cross-sections at 48 hpf. Arrows indicate mislocalized ccnd1 expression.

(B) Immunostaining of cleaved Caspase3 in g9a or znf644b morphant midbrain cross-sections at 72 hpf and rescue by p53-MO (n = 3 in each group). Arrows denote the position of Caspase3+ cells.

(C) Immunostaining of PCNA in WT or znf644a morphant midbrain cross-sections (n = 3 in each group). Arrows denote the position of PCNA+ cells.

Expression Data

Gene:	ccnd1
Fish:	AB AB + MO1-znf644a AB + MO1-znf644b
Knockdown Reagents:	MO1-znf644a MO1-znf644b
Anatomical Term:	midbrain
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-ehmt2 AB + MO1-znf644a AB + MO1-znf644b
Knockdown Reagents:	MO1-ehmt2 MO1-znf644a MO1-znf644b
Observed In:	cell proliferation in midbrain midbrain midbrain apoptotic process
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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