FIGURE

Fig. S6

ID
ZDB-FIG-160108-6
Publication
Tuttle et al., 2014 - Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration
Other Figures
All Figure Page
Back to All Figure Page
Fig. S6

Enlarged early endosomes grow and accumulate over time in NC cells of rbc3a-MO1-injected embryos. Confocal images of sox10:gfp+ NC cells (bottom row, green) double labeled with anti-EEA1 (A-F, red) and anti-Rab11a (A′-F′, blue), which marks late endosomes. (A′′-F′′) Merged images of EEA1, Rab11a, and sox10:gfp fluorescence. EEA1+ vesicles increase in number and size in rbc3a-MO1-injected embryos from 14-20 hpf compared to wild-type controls, while Rab11a+ vesicles show no change. Scale bars, 10 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 10-13 somites to 20-25 somites

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.