FIGURE

Fig. 3

ID
ZDB-FIG-151019-12
Publication
Sztal et al., 2015 - Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function
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Fig. 3

Formation of nemaline bodies and aggregates in Tg(ACTA1 D286G-eGFP)high zebrafish. a Maximum projection images from time lapse of Tg(ACTA1D286G-eGFP)high fish from 56 to 71 hpf showing nemaline bodies distributed throughout the skeletal muscle (arrows). Nemaline bodies’ fragment from 59.5 hpf (arrows), coincident with the formation of aggregates at the myosepta (arrowheads). b Quantification of the mean number of nemaline bodies in Tg(ACTA1 D286G-eGFP) low (n = 50 per stage) and Tg(ACTA1 D286G-eGFP) (n = 48 per stage) strains. c Quantification of the percentage of fish displaying globular aggregates in Tg(ACTA1 D286G-eGFP) low and Tg(ACTA1 D286G-eGFP) high strains (n = 50 per stage). Error bars represent SEM from three independent experiments (n = 45 per replicate)

Expression Data
Gene:
Fish:
Anatomical Terms:
Stage Range: Long-pec to Pec-fin

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Long-pec to Day 5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Acta Neuropathol.